Latest Insights on Sake: Unveiling GABA Activation for Ultimate Relaxation and Calmness

The Hidden Power of Japanese Sake


In collaboration with Kinki University, the researchers have uncovered that specific compounds in Japanese sake activate the GABA receptor. Alcohol's impact on brain nerve cells is known to induce drunkenness, with a distinctive relaxation effect. This effect is attributed to the activation of the neuronal GABA receptor by both GABA and alcohol.


Japanese sake, with its myriad compounds, presents an intriguing possibility—there could be compounds beyond the known ones influencing the GABA receptor. Through metabolome analysis, the team identified organic acids in sake that activate the GABA receptor, as demonstrated in Xenopus oocytes.


Taking the exploration further, the researchers tested the anti-anxiety effects of these organic acids on mouse behavior using the elevated plus-maze test. The findings were significant, with certain compounds exhibiting notable anxiolytic effects. This research sheds light on a new dimension of Japanese sake's impact and opens avenues for potential therapeutic applications.


Enjoy the Relaxing Effect of Sake


Experience the science behind the soothing properties of sake with the latest research revealing the GABA activation for relaxation and calmness. Delve into the intricate world of junmai ginjo-shu, where the aromatic notes and delicate flavors intertwine.


Explore the nuanced balance of flavors in Hana Kizakura Junmai Ginjo, enhanced by the use of Kizakura (yellow cherry blossom) flower yeast. With its refreshing sweetness and gentle taste, this sake, boasting a slightly low alcohol content of 12%, emerges as a delightful elixir for relaxation. Cheers to the harmony of tradition and science in every sip!

让我们探索 花 黄樱纯米吟酿的微妙平衡,使用黄樱 (黄色樱花)花酵母增强味道吧。其口感清爽的甜味和柔和,酒精含量略低,为12%,是一种令人愉快的放松良药。它每一口都为传统与科学的和谐干杯!